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DHEA - 50mg
It is the most abundant hormone in humans and other mammals,
and DHEA , it plays a critical role in many different bodily
functions. In fact, decrease in DHEA levels is being increasingly
used as an indicator of reduced immune response, loss of libido
and lack of a sense of general wellbeing. Clinical studies over
the past ten years show that DHEA may be the most critical single
chemical in predicting health and disease.
The body produces DHEA in the adrenal gland using cholesterol
as the starting material. It is metabolized to androstenedione,
which is converted directly to testosterone. Like testosterone
(estrogen in women) and other critical hormones, DHEA levels
peak in the second or third decade of life, after which the decline
begins. In men, roughly one-half of DHEA is lost by age 40. Reduced
levels of DHEA mean reduced amounts of androstenedione, testosterone
and other steroid hormone metabolites. It is interesting to note
that as cholesterol in general increases with age, DHEA levels
decrease. As a result, DHEA deficiency is associated with an
array of chronic conditions, such as obesity, diabetes, high
blood pressure, coronary artery disease, and various immune deficiencies,
including autoimmune diseases.
DHEA directly affects glucose metabolism. High blood glucose
inhibits growth hormone (GH) and low blood glucose stimulates
growth hormone. Stimulation of growth hormone is beneficial to
DHEA, because it suppresses insulin. By the same token, fasting
increases both GH and DHEA. Thus, the importance of DHEA in intense
exercise and endurance training can hardly be overemphasized.
In fact, Dr. William Regelson of Medical College of Virginia
in his book The Superhormone Promise calls DHEA "the superstar
of hormones" and "one of the most powerful tools" available
for enhancing and extending life.
Clinical results show that oral supplementation with DHEA can
have numerous beneficial effects including:
- Feelings of energy and wellbeing.
- Improved insulin sensitivity and glucose tolerance.
- Reduced risk of coronary artery diseases.
- Lower obesity/waist-to-hip ratio.
- Enhanced libido.
- Reduced depression and increases cognitive ability.
- Regelson, W. and Colman, C., The
Superhormone Promise, New York: Simon & Schuster, 1996.
- Morales et al., "Effects of Replacenment Dose of Dehydroepiandrosterone
in Men ands Women in Advancing Age," J. Clin. Endocrinol.
Metab.: 78, 1360, 1994
- Barrett-Conner, E. & Ferra, A., "Dehydroepiandrosterone,
Dehydroepiandrosterone Sulfate, Obesity, Waste-Hip Ration,a nd
Noninsulin-Dependent Diabetes in Postmenopausal Women: The Rancho
Bernardo Study," J. Clin. Endocrinol. Metab.: 81, 59,
- Wolkwowitz et al., "Antidepressant and Cognition-Enhancing
Effects of DHEA," Ann. N. Y. Acad. Sci.: 774, 337, 1995.
- Alexandersen et al., "The Relationship of Natural Androgens
to Coronary Heart Disease in Males: A Review," Atherosclerosis:
125, 1, 1997.
- Shealy, C., "DHEA: The Youth and Health Hormone," Comnnecticut:
Keats Publishing, 1996